Mind Medicine Inc. (NEO: MMED), more commonly known as MindMed, announced on Tuesday that the first patient has been dosed in a Phase 1 investigator-initiated study aimed to evaluate the effects of MDMA-like substances. The study is being led by the firm’s collaborator and the program’s principal investigator, Dr. Matthias Liechti at University Hospital Basel.
The trial involves 24 healthy subjects who will randomly receive doses of MDMA or MDMA-like substances like MDA, Lys-MDMA, and Lys-MDA, while the rest will get placebo treatments. The study aims to assess the subjective effects of the various drugs for future application of the substance in treating disorders.
“By using pharmacokinetics and modern psychological and psychometric tests, this study will investigate the potential to better control the bioavailability, slow the effect onset and reduce possible adverse effects of MDMA and MDA by using these prodrugs,” said Dr. Liechti.
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The principal investigator also said the study will investigate the “effects of MDA in direct comparison with MDMA for the first time in humans.”
Executive President Dr. Miri Halperin Wernli added that the study “will enhance our understanding of the therapeutic properties involved in the induction of positive mood in a way that may help optimize the treatment model for our R(-)-MDMA drug candidate.”
The firm started in October 2021 to develop R(-)-MDMA for treating symptoms related to autism spectrum disorder.
Mind Medicine Inc. last traded at $9.35 on the NEO.
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